Chemistry
Chemistry is the natural science concerned with the composition, structure and properties of substances, the changes they undergo, and the energy involved in those changes. By studying atoms, molecules and their interactions, chemists explain material behaviour and develop ways to identify, make and improve substances. The field spans areas from medicines and biological processes to materials, manufacturing and environmental analysis, while also examining how chemical products and processes can be made safer.
Scope and basic concepts
Chemistry examines matter at the level of elements, compounds and mixtures: what substances contain, how their particles are arranged, which properties follow from that structure, and how substances interact. Atoms are the basic units of chemical elements; atoms can join into molecules or extended structures. Their rearrangement in a chemical reaction produces different substances. A physical change, such as water freezing, changes a material's state without changing its chemical identity, whereas a chemical reaction changes the substances present. Chemists also track the energy absorbed or released as transformations occur.
Evidence, measurement and models
Chemistry combines observation and experiment with quantitative measurement. Researchers may analyse a sample to identify its components and their amounts, investigate a material's properties, or synthesize a substance under controlled conditions. Because particles such as atoms and molecules are generally too small to observe directly, chemists use models to connect measurable, large-scale behaviour with proposed microscopic structure. Chemical symbols, formulae and equations provide a compact language for representing elements, substances and reactions. Experimental results test these representations and can require a theory or model to be revised.
Major areas of chemistry
Chemistry is divided into overlapping specialties rather than a single exhaustive list. Organic chemistry studies carbon-containing compounds; inorganic chemistry focuses on many other compounds and materials, including metals and minerals. Analytical chemistry develops ways to determine what a sample contains and in what quantities. Physical chemistry applies physical principles and mathematical methods to molecular behaviour, reaction rates and energy changes. Biochemistry investigates substances and reactions in living systems. Materials, environmental, medicinal and industrial chemistry address particular materials, applications or settings. Chemical engineering works closely with chemistry to design and scale processes for making products.
From practical crafts to a modern science
People used chemical processes long before chemistry became a formal science: cooking, fermentation, pottery, dyeing and metalworking all involve transforming materials. For centuries, practical work coexisted with speculative accounts of what matter was made of. In the eighteenth century, systematic experiments and careful weighing helped establish a more quantitative discipline. Antoine-Laurent Lavoisier's work challenged phlogiston explanations of combustion and helped popularize conservation of mass: in ordinary chemical transformations, matter is rearranged rather than created or destroyed. This approach made precise measurement and reproducible analysis central to chemical research.
Uses, risks and responsible design
Chemical knowledge supports the analysis of food, water and other materials; the development of medicines, fuels, fertilizers and polymers; and explanations of processes in living organisms. These uses can improve health and everyday life, but chemical production and disposal can also create hazardous substances and pollution. Green chemistry responds by designing chemical products and processes to prevent or reduce hazardous substances at their source, considering stages from design and manufacture through use and disposal. This differs from remediation, which treats waste or cleans up releases after hazardous substances have been generated.
Key facts
- Field
- A natural science studying substances, their properties and structure, their transformations, and associated energy changes.
- Scale
- Connects observable material behaviour with the composition and interactions of atoms and molecules.
- Approach
- Uses observation, experimentation, measurement, analysis, synthesis and models.
- Major specialties
- Include organic, inorganic, analytical, physical and biological chemistry, among many others.
- Green chemistry
- Designs products and processes to reduce or eliminate hazardous substances across their life cycle.
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References
- 1.Chemistry Definition, Topics, Types, History, & Facts
Encyclopaedia Britannica · encyclopedia · reliability: high · retrieved 12 October 2026
Supports: Overview of chemistry's scope, matter and chemical transformations, specializations, history and applications.
- 2.Areas of Chemistry
American Chemical Society · other · reliability: high · retrieved 12 October 2026
Supports: Descriptions of analytical, biochemical, inorganic, organic and physical chemistry and adjacent chemical-engineering work.
- 3.1.1 Chemistry in Context
OpenStax, Rice University · other · reliability: high · retrieved 12 October 2026
Supports: Educational account of chemistry's historical development, scientific method, chemical change and its everyday context.
- 4.Antoine-Laurent Lavoisier
Science History Institute · other · reliability: high · retrieved 12 October 2026
Supports: Historical context for Lavoisier's experiments, precise measurement and popularization of conservation of mass.
- 5.Basics of Green Chemistry
United States Environmental Protection Agency · other · reliability: high · retrieved 12 October 2026
Supports: Definition of green chemistry and its focus on reducing or eliminating hazardous substances through product and process design.
References are suggested by the research engine and may be incomplete. Unverified URLs are omitted rather than guessed.
Article history
- Version 112 October 2026 · EditorCreated by Zapia